Artigo do Dr. Juruena que aponta a relaçoa de depressao e a hipofunçao dos receptores de glico e mineralocorticoides no cerebro.
Enhanced cortisol action in the brain might prove to be a successful approach to maximise therapeutic antidepressant effects. Hypotheses regarding the mechanism of these receptor changes involve non-steroid compounds that regulate GR function via second messenger pathways. Research in this field will lead to new insights into the pathophysiology and treatment of affective disorders.
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